Fig. 7.

FA suppresses the activation of NLRP3 inflammasome, increase of ROS, and SOD clearance caused by 18 Gy in vitro. (A-B) Measurement of ROS production after radiation using flow cytometry. (C) Detection of SOD clearance. (D) Measurement of cell proliferation after radiation using CCK8 assay. (E-H) Measurement of NLRP3, IL-1β, pro-IL-1β, IL-18 secretion by cells. (I-N) Western blotting analysis of NLRP3, caspase-1, IL-1β, pro-IL-1β, IL-18 protein expression in HaCaT cells. * p < 0.05, ** p < 0.01, *** p < 0.001 compared with the 18 Gy group. # p < 0.05, ### p < 0.001 compared with the control group