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. 1987 Oct;40(10):1221–1227. doi: 10.1136/jcp.40.10.1221

Mefenamic acid enteropathy.

P E Isaacs 1, G E Sladen 1, I Filipe 1
PMCID: PMC1141199  PMID: 3680546

Abstract

The clinical, radiological, and histological features of two patients with severe intestinal damage induced by mefenamic acid and mimicking coeliac disease are described. Symptoms rapidly reverted on withdrawal of the drug, and in one case, did not relapse during treatment with other non-steroidal anti-inflammatory drugs.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Chadwick R. G., Hossenbocus A., Colin-Jones D. G. Letter: Steatorrhoea complicating therapy with mefenamic acid. Br Med J. 1976 Feb 14;1(6006):397–397. doi: 10.1136/bmj.1.6006.397-b. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Enteritis and colitis associated with mefenamic acid. Br Med J (Clin Res Ed) 1983 Nov 26;287(6405):1626–1627. doi: 10.1136/bmj.287.6405.1626. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Hawkey C. J., Rampton D. S. Prostaglandins and the gastrointestinal mucosa: are they important in its function, disease, or treatment? Gastroenterology. 1985 Nov;89(5):1162–1188. doi: 10.1016/0016-5085(85)90225-2. [DOI] [PubMed] [Google Scholar]
  4. Leung A. C. Thrombosis in systemic lupus erythematosus. Br Med J (Clin Res Ed) 1983 Nov 26;287(6405):1628–1628. doi: 10.1136/bmj.287.6405.1628-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Lewis J. H. Gastrointestinal injury due to medicinal agents. Am J Gastroenterol. 1986 Sep;81(9):819–834. [PubMed] [Google Scholar]
  6. Marks J. S., Gleeson M. H. Steatorrhoea complicating therapy with mefenamic acid. Br Med J. 1975 Nov 22;4(5994):442–442. doi: 10.1136/bmj.4.5994.442-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Robertson C. E., Ford M. J., Van Someren V., Dlugolecka M., Prescott L. F. Mefenamic acid nephropathy. Lancet. 1980 Aug 2;2(8188):232–233. doi: 10.1016/s0140-6736(80)90122-1. [DOI] [PubMed] [Google Scholar]
  8. VanWalraven A. A., Edels M., Fong S. Pancreatitis caused by mefenamic acid. Can Med Assoc J. 1982 Apr 15;126(8):894–894. [PMC free article] [PubMed] [Google Scholar]

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