Table 2.
Univariate and Multivariable analysis of overall reinfection in non-hospitalized patients over one-year old with a history of hospitalization due to COVID-19
| Patient characteristics | Reinfection Rate (per 1000) | Crude Hazard Ratio (95%CI) | P_value | Adjusted Hazard Ratio (95%CI) | P_value |
|---|---|---|---|---|---|
| Age (years) | |||||
| 1–18 | 73.86 | Reference | - | Reference | - |
| 19–44 | 156.002 |
2.33 (1.02–5.32) |
0.043 |
3.93 (1.24–12.41) |
0.030 |
| 45–64 | 135.97 |
1.97 (0.86–4.50) |
0.104 |
3.40 (1.08–10.68) |
0.046 |
| ≥ 65 | 89.23 |
1.30 (0.56–3.02) |
0.537 |
1.82 (0.56–5.83) |
0.359 |
| Sex | |||||
| Female | 139.22 | Reference | - | Reference | - |
| Male | 105.94 |
0.75 (0.55- 1.00) |
0.054 |
0.77 (0.56–1.05) |
0.065 |
| Job types | |||||
| Unrelated to healthcare and medical | 118.82 | Reference | - | Reference | - |
| Healthcare worker | 77.89 |
0.74 (0.18–2.98) |
0.678 |
0.93 (0.22–3.95) |
0.846 |
| COVID-19 related health care worker | 345.16 |
3.49 (1.89–6.43) |
< 0.001 |
3.67 (1.77–7.61) |
< 0.001 |
| Cough* | |||||
| No | 109.25 | Reference | - | Reference | - |
| Yes | 141.11 |
1.33 (0.99–1.80) |
0.056 |
1.26 (0.93–1.71) |
0.109 |
| Fever* | |||||
| No | 116.86 | Reference | - | Reference | - |
| Yes | 136.86 |
1.23 (0.91–1.67) |
0.178 |
1.14 (0.83–1.56) |
0.358 |
| PaO2 (mmHg)* | |||||
| < 93 | 138.30 | Reference | - | Reference | - |
| ≥ 93 | 108.52 |
0.80 (0.59–1.08) |
0.149 |
0.65 (0.47–0.91) |
0.007 |
| Respiratory distress* | |||||
| No | 128.99 | Reference | - | Reference | - |
| Yes | 114.44 |
0.84 (0.62–1.14) |
0.266 |
0.82 (0.59–1.14) |
0.235 |
| Muscular pain* | |||||
| No | 116.32 | Reference | - | Reference | - |
| Yes | 136.91 |
1.15 (0.85–1.57) |
0.351 |
1.06 (0.76- 1.47) |
0.660 |
| Comorbidity score | |||||
| 0 | 138.12 | Reference | - | Reference | - |
| 1 | 88.34 |
0.62 (0.41–0.94) |
0.025 |
0.58 (0.38–0.91) |
0.012 |
| 2 | 102.54 |
0.74 (0.42–1.29) |
0.298 |
0.67 (0.37–1.21) |
0.207 |
| 3 | 46.38 |
0.30 (0.04–2.20) |
0.239 |
0.49 (0.07–3.65) |
0.423 |
| Vaccination status | |||||
| Lower than two doses | 195.97 | Reference | - | Reference | - |
| Two or more than two doses | 70.67 |
0.33 (0.24–0.45) |
< 0.001 |
0.21 (0.15–0.30) |
< 0.001 |
*At the time of first hospitalization and initial infection
PaO2: partial pressure of oxygen