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. 2024 Sep 14;12:150. doi: 10.1186/s40478-024-01859-z

Table 3.

Top 13 upregulated genes in the Y-33075 treated group versus the control solvent group

Gene ID Gene name log2 Fold change padj
Nrn1 Neuritin 1 4.223 1.47E-46
Ciart Circadian associated repressor of transcription 3.523 2.64E-90
Prph Peripherin 2.983 3.16E-115
Lamb3 Laminin subunit beta 3 2.851 5.50E-12
Trarg1 Trafficking regulator of GLUT4 2.826 9.82E-88
Rbpms2 RNA binding protein mRNA processing factor 2 2.777 2.96E-60
Rbpms RNA binding protein mRNA processing factor 2.757 5.99E-89
Tppp3 Tubulin polymerization-promoting protein family member 3 2.463 4.75E-59
Slc17a6 Solute carrier family 17 member 6 2.429 3.56E-64
Fosl1 FOS like 1 AP-1 transcription factor subunit 2.198 6.58E-15
Nefh Neurofilament heavy chain 2.074 1.08E-17
Rgs5 Regulator of G-protein signaling 5 2.037 9.56E-43
Nell2 Neural EGFL like 2 2.016 3.08E-87

Upregulated genes in the Y-33075 exposed group at DEV 4 versus the control solvent group ranked by the binary logarithm of fold change (log2FC). For each gene identifier, the name, log2FC, and adjusted p-value (padj) are presented.