Fig. 4. Long-term serial microCT imaging of the murine ductal tree with different contrast agents in 70% ethanol.
Abdominal mammary glands were injected with 40 μl of indicated contrast agent in 70% ethanol: Omnipaque (90 mg I/ml), MVivo Au (60 mg Au/ml), TaOx (10.8 mg Ta/ml), Fenestra VC (15 mg I/ml), MVivo BIS (45 mg Bis/ml). 3D reconstruction of manually segmented regions of interest (i.e., ipsi- and contralateral abdominal mammary glands) of the same animals is shown at different imaging time points from immediately after (D0) last ID injection to 60 days (D60). 3D reconstruction was thresholded to include only voxels with a HU value of >300. Scale bar is 1 mm.