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RT activity of recombinant clones of B495, B497, and B670. RT activity was determined in PBMC culture supernatants at the peak of replication and normalized to p24 antigen concentration. Regression lines show the correlation of viral RT activity with replicative capacity. PR-RTB497,12 is not represented due to limited replication and RT activity outside the assay range. The data are from one of two independent experiments in which comparable results were obtained.
