Table 1.
Landomycin A biosynthetic genes and proposed functions of their products16
| Genes | Proposed function | Genes | Proposed function |
|---|---|---|---|
|
| |||
| lanE | Oxygenase | lanU | unknown |
| lanF | Cyclase (CYC) | lanV | reductase |
| lanA | ketoacyl synthase (KSα) | lanGT2 | glycosyltransferase |
| lanB | chain length factor (KSβ) | lanX | unknown |
| lanC | acyl carrier protein (ACP) | lanGT1 | glycosyltransferase |
| land | reductase | lanK | regulatory gene |
| lanL | Cyclase (CYC) | lanJ | transporter gene |
| lanM2 | oxidoreductase | lanZ1 | NDP-hexose 3,5-epimerase |
| lanO | reductase | lanGT3 | glycosyltransferase |
| lanP | decarboxylase | lanZ2 | NDP-hexose synthase |
| lanG | NDP-hexose synthase | lanZ3 | NDP-hexose 4-ketoreductase |
| lanH | NDP-hexose 4,6-dehydratase | lanGT4 | glycosyltransferase |
| lanQ | NDP-hexose 3,4-dehydratase | lanZ4 | reductase |
| lanR | NDP-hexose 4-ketoreductase | lanZ5 | oxygenase |
| lanS | NDP-hexose 2,3-dehydratase | lanZ6 | unknown |
| lanT | oxidoreductase | ||