Fig 2. Cows develop serum broadly neutralizing antibody responses following immunization with recombinant trimers.

Longitudinal samples were collected and tested for cow-485 and cow-488 on the 12-virus global panel. Neutralization ID₅₀ titers are presented for each virus by color for each time point. Vertical dotted lines represent prime and boost dates; immunogen colors are described in Fig 1A. Percent breadth is represented by a black line whose y-axis is shown on the right. ID₅₀ values are shown as 1/dilution on the y-axis.