Fig 4. Characteristics of sorted cow antibodies according to CDRH3 length.

(A) Sort-enriched isolated CDRH3 lengths were grouped into bars to show the ratio of those with DY/YD motifs. Short CDRH3 length antibodies are shown in yellow, long in pink, and ultralong in purple. Bars are outlined in red for cow-485 and blue for cow-488. (B) Pie charts representing the total antibodies isolated and tested are shown and categorized by CDRH3 length. Colors indicate antibodies that did not express in black, those that bound to BG505 SOSIP using ELISA in pink, and those that were determined to have cross-clade neutralization in teal. The number in the middle of the graph represents the total isolated and tested antibodies.