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. 2024 Sep 19;19(9):e0310524. doi: 10.1371/journal.pone.0310524

Fig 4. Inflammation infiltrations were initiated surrounding AAT globules or pericentral area.

Fig 4

Representative images of immunohistochemical staining of 2C1 in the liver section of untreated and BBR-treated Pi*Z mice. (A) AAT globule-surrounding infiltrations were observed in the liver of both untreated and BBR-treated Pi*Z mice. (B, C) Inflammatory infiltrations initiated at pericentral areas (zone 3) in the liver sections of BBR-treated Pi*Z mice. These infiltrations are colocalized with 2C1-positive hepatocytes. (D) Inflammatory infiltration in the liver section from a BBR-treated Pi*Z mouse. Some infiltratory cells were 2C1-positive.