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. 2024 Sep 19;19(9):e0310524. doi: 10.1371/journal.pone.0310524

Fig 9. BBR potentiated liver inflammation only in Pi*Z mice.

Fig 9

WT, Pi*M and Pi*Z transgenic mice were treated with 50 mg/kg/day of BBR or solvent only for 30 days. The sample size was as follows: WT control n = 3, WT BBR n = 3, Pi*M control n = 5, Pi*M BBR n = 6, Pi*Z control n = 5, and Pi*Z BBR n = 9. H&E staining was performed on the liver section. Representative images of (A) WT control, (B) WT BBR, (C) Pi*M control, (D) Pi*M BBR, (E) Pi*Z control, (F, G) Pi*Z BBR. (H) Quantification of the percentages of infiltrated area in the liver. Arrow indicates inflammation focus.