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. 2024 Sep 6;15:1413704. doi: 10.3389/fimmu.2024.1413704

Figure 4.

Figure 4

DRE in APOL6 3’ UTR and its potential cis-regulatory effects. (A) The Venn diagram of 3’ UTR DRE genes and cis-regulated genes. (B) The Venn diagram of 3’ UTR DRE genes and DEGs. (C–E) APOL6:chr22:35660499/35660551 editing level (C, D) and gene expression level (E). (F, G) Correlation of cis-regulated APOL6 gene expression level and editing sites (APOL6:chr22:35660499/35660551). (H–J) CTSS:chr1:150732177/150732184 RNA editing level (H, I) and gene expression level (J). (K, L) Correlation of cis-regulated CTSS gene expression level and editing sites (CTSS:chr1:150732177/150732184). (M, N) The RNA secondary structure at the WT (M) and edited (N) of CTSS:chr1:150732177/150732184. ***P < 0.001, ****P < 0.0001.