Fig. 2.

Basal electrophysiology in male and female mouse left atria. (A) Exemplar ensemble averaged optical action potential traces, indicating APD₇₀ measurement point in male and female left atria. (B) APD₇₀ maps of tissue paced at 100 ms cycle length. (C) Mean APD₇₀ across 80, 100 and 120 ms paced cycle lengths. (D) APD₇₀ spatial heterogeneity at 100 ms cycle length. (E) Exemplar activation maps from male and female left atria at 100 ms cycle length. (F) Mean conduction velocity of tissue paced at 100 ms cycle length. (G) Male and female conduction velocity spatial heterogeneity (100 ms cycle length). Statistical analysis was conducted using two-way repeated measures ANOVA across different cycle lengths and unpaired t-tests at single 100 ms cycle length. †P < 0.05 between sexes and ^#P < 0.05 indicates cycle length effect; n = 18 and n = 20 for male and female, respectively.