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. 2024 May 13;14(9):3818–3833. doi: 10.1016/j.apsb.2024.05.013

Table 2.

Targets, names, and sequences of representative peptides targeting immune checkpoints.

Target Peptide name Sequence Ref.
PD-1 NP-12 H-SNTSESFK(H-SNTSESF)FRVTQLAPKAQIKE-NH2 92
PD-L1 CLP002 WHRSYYTWNLNT 93
DPPA-1 H-nyskptdrqyhf-NH2a 94
OPBP-1 gqsehhmrvysfa 95
CTLA-4 ERY2-4 Ac-C1AWGQAILEGELAWLEGGGGGAGQLADLKRQLAWWKQAC1-NH2b 99
TIGIT DTBP-3 H-ggytfhwhrlnp-NH2a 106
BTLA HVEM(14–39) Ac-ESC1PKC2SPGYRVKEAC1GELTGTVC2EP-NH2b 108
HVEM gD (1–36)(K10C–T29C) Ac-KYALVDASLC1MADPNRFRGKDLPVLDQLC1DPPGVRR-NH2b 110
VISTA AP1049 H-SSAC1DWIKRSC1H-NH2b 115
LAG-3 C25 H-C1VPMTYRAC1b-OH 118
CD47 Pep-20 AWSATWSNYWRH 122
a

Lowercase letters indicate d-amino acids.

b

Cn: two cysteines with the same number form a corresponding disulfide bond.