Table 1.
Proportion of seropositivity of participants on the dose–response study 10 years after vaccination, by vaccine group.
| Group | Total | Seropositive participants* |
Comparison to the reference vaccine |
||
|---|---|---|---|---|---|
| N | n | % | Difference of SP | 95 % CI | |
| 27.476 IU | 59 | 49 | 83.1 | − | − |
| 10.447 IU | 40 | 36 | 90.0 | 6.9 | (−6.4; 20.3) |
| 3.013 IU | 54 | 47 | 87.0 | 4.0 | (−9.1; 17.1) |
| 587 IU | 43 | 40 | 93.0 | 10.0 | (−2.3; 22.2) |
| 158 IU | 37 | 31 | 83.8 | 0.7 | (−14.5; 16.0) |
| 31 IU | 20 | 17 | 85.0 | 1.9 | (−16.4; 20.3) |
*
P-value (Fisher’s exact test) = 0.700. SP: neutralizing antibodies ≥ 3.15 Log10 mIU/mL. Difference of SP: Difference of seropositivity (reduced dose – standard dose).