Figure 1. The cluster analysis of differential metabolites. PCA score plot of cell metabolite clustering in H460, H460_met, H460_KO_met, and quality control (QC) groups in negative (A) and positive (B) ion mode, respectively. Cluster analysis of differentially expressed metabolites among the three groups in negative (C) and positive (D) ion mode, respectively. Key: H460: H460 cell samples; H460_met: metformin-treated H460 cell samples, H460_KO_met: metformin-treated Axin1-/- H460 cell samples.
