Table 2.
Basic biochemistry characteristics of the study population.
| Variables | MTHFR rs1801133 carriers (N=1624) | Non-carriers (n=1879) | P value | |||
|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | |||
| Biochemistry (Mean/SD)a | ||||||
| Total cholesterol (mg/dL) | 192.68 | 43.31 | 195.9 | 45.58 | 0.0428 | |
| HDL (mg/dL) | 60.5 | 18.11 | 59.64 | 17.67 | 0.3039 | |
| LDL (mg/dL) | 115.01 | 36.69 | 116 | 37.43 | 0.479 | |
| Triglyceride (mg/dL) | 127.69 | 98.44 | 133.06 | 124.45 | 0.1771 | |
| Platelet (x10^3/uL) | 246.12 | 75.4 | 244.32 | 81.04 | 0.5011 | |
| D-dimer (mg/l FEU) | 22.58 | 93.21 | 39.25 | 156.44 | 0.0543 | |
| Protein C (%) | 111.2 | 19.59 | 112 | 39.3 | 0.9549 | |
| Protein S (%) | 76.6 | 13.21 | 89.6 | 24.62 | 0.3148 | |
| Antithrombin III (%) | 94.83 | 15.73 | 74.33 | 22.37 | 0.1489 | |
| HbA1c (%) | 6.24 | 1.51 | 6.26 | 1.48 | 0.6683 | |
| Fasting glucose (mg/dL) | 108.96 | 40.34 | 110.21 | 35.26 | 0.3995 | |
| TSH (uIU/mL) | 2.98 | 12.16 | 3.03 | 13.22 | 0.9283 | |
| Free T4 (ng/dL) | 9.62 | 6.52 | 9.66 | 5.83 | 0.8765 | |
| T4 (ug/dL) | 9.23 | 21.74 | 7.42 | 2.06 | 0.4004 | |
| T3 (ng/dL) | 81.11 | 42.5 | 84.43 | 57.8 | 0.4956 | |
| Alk-p (U/L) | 96.89 | 58.87 | 97.93 | 69.21 | 0.6903 | |
| Hb (g/dL) | 12.74 | 1.8 | 12.75 | 1.89 | 0.856 | |
| MCV (fL) | 90.14 | 7.81 | 89.78 | 7.92 | 0.1968 | |
| Folic acid (ng/mL) | 13.49 | 7.83 | 14.25 | 8.21 | 0.2521 | |
aContinuous variables were expressed as mean ± standard deviation (SD) and were analyzed using Student's t-test for normal data distributions