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. 2024 Aug 19;21(12):2261–2271. doi: 10.7150/ijms.97524

Table 5.

Factors associated with major and hip fractures of the study population.

Major fracture OR 95% CI P valuec
Age
<55 1
>=55 6.361 3.255-12.431 <0.0001
Sex
Male 1
Female 1.009 0.763-1.334 <0.9497
FRAX-majora 1.057 1.042-1.071 <0.0001
MTHFR rs1801133
GG 1
GA 0.852 0.657-1.103 0.2241
AA 1.198 0.78-1.84 0.4104
Hip fracture OR 95% CI P valuec
Age
<55 1
>=55 8.075 1.981-32.917 0.0036
Sex
Male 1
Female 0.635 0.403-0.999 0.0495
FRAX-hipb 1.077 1.051-1.104 <0.0001
MTHFR rs1801133
GG 1
GA 0.891 0.564-1.408 0.6211
AA 1.031 0.462-2.303 0.9407

aFRAX-major risk exceeding 20% vs. FRAX-major risk below 20%.

bFRAX-hip risk exceeding 3% vs. FRAX-hip risk below 3%.

cBy logistic regression with adjustment of age, sex, and FRAX.