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. 2024 Aug 19;21(12):2261–2271. doi: 10.7150/ijms.97524

Table 7.

Factors associated with major and hip fractures in females.

Major fracture OR 95% CI P valuec
Age 1.066 1.052-1.08 <0.0001
Sex, female
<55 1
>=55 5.011 2.55-9.844 <0.0001
FRAX-majora 1.069 1.051-1.086 <0.0001
MTHFR rs1801133
GG 1
GA 0.821 0.608-1.108 0.198
AA 1.236 0.759-2.015 0.3943
Hip fracture OR 95% CI P valuec
Age 1.084 1.057-1.111 <0.0001
Sex, female
<55 1
>=55 5.568 1.353-22.906 0.0174
FRAX-hipb 1.09 1.059-1.121 <0.0001
MTHFR rs1801133
GG 1
GA 0.754 0.429-1.326 0.3274
AA 0.607 0.185-1.992 0.4104

aFRAX-major risk exceeding 20% vs. FRAX-major risk below 20%.

bFRAX-hip risk exceeding 3% vs. FRAX-hip risk below 3%.

cBy logistic regression with adjustment of age, sex, and FRAX.