Table 2.
Stratification analysis of herpes zoster in total knee replacement patients
| Cases occurring new-onset herpes zoster | |||
|---|---|---|---|
| Subgroups | Total knee replacement cohort (No. of event/ Total knee replacement patient amount in each subgroup) |
Control cohort (No. of event/ non-total knee replacement patient amount in each subgroup) |
HR (95% CI)a,b |
| Gender | |||
| Male | 181/16851 | 160/16851 | 1.097 (0.887,1.357) |
| Female | 461/26721 | 392/26721 | 1.146 (1.001,1.311) |
| Age at index date | |||
| 18-49 years oldc | ≤ 10/373 | ≤ 10/373 | 0.463 (0.116,1.853) |
| 50-64 years old | 78/6149 | 62/6149 | 1.245 (0.892,1.737) |
| ≥ 65 years old | 592/38492 | 486/38492 | 1.187 (1.052,1.338) |
a Propensity score matching was performed on age at index, sex, race, body mass index, lab data, status of comorbidities, lifestyle, socioeconomic issues, medical utilization status, vaccination for herpes zoster status.
b Follow-up time in all analyses in this table was set as 5-years, starting from 90 days after index date
c In order to protect privacy of individuals, in the TriNetX research network, if the patient amount is less or equal to 10, results show the count as 10