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. 2024 Sep 19;24:609. doi: 10.1186/s12884-024-06800-9

Table 4.

Prevalence of preeclampsia and sFlt-1/PIGF ratio by maternal SARS-CoV-2 serostatus in study participants

SARS-CoV-2
seronegative
n (%)
N = 32
SARS-CoV-2
seropositive
n (%)
N = 68
p-value OR [95%CI] p-valuec
Clinical Preeclampsia, (N= 100) 0.209a 1.8 [0.73 – 4.26] 0.207
No 15 (41.7) 19 (59.4)
Yes 17 (27.9) 49 (72.1)
sFlt-1/PIGF ratio, (N= 100)
Median (IQR) 58.2 (2.19–1163.7) 131.8 (0.4–2439) 0.205b 1.01 [0.99- 1.002] 0.199
Normal/Low (< 38) 13 (38.2) 21 (61.8) 0.337a 1.5 [0.64 – 3.67] 0.339
Moderate to high (≥ 38) 19 (28.8) 47 (71.2)

aChi-square

bWilcoxon rank sum test

cLogistic regression

sFlt-1 soluble Fms-like tyrosine kinase 1; PIGF- Placenta growth factor