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. 2024 Sep 19;23:303. doi: 10.1186/s12944-024-02286-8

Table 6.

Exploratory subgroup analysis of the association between RC (per SD increase) and reversion to normoglycemia

Characteristic No. of participants HR (95% CI) P value P for interaction
Gender 0.213
 Male 9173 0.80 (0.77, 0.83) < 0.001
 Female 5306 0.77 (0.73, 0.81) < 0.001
Age, years < 0.001
 < 30 799 0.78 (0.68, 0.89) < 0.001
 30–45 4785 0.82 (0.78, 0.87) < 0.001
 45–60 5647 0.80 (0.76, 0.84) < 0.001
 ≥ 60 3788 0.70 (0.65, 0.76) < 0.001
BMI, kg/m2 0.158
 < 24 6115 0.73 (0.70, 0.77) < 0.001
 24–28 2411 0.82 (0.78, 0.86) < 0.001
 ≥ 28 6493 0.87 (0.80, 0.95) < 0.001
TG, mmol/L 0.441
 < 1.7 9147 0.75 (0.71, 0.78) < 0.001
 ≥ 1.7 5871 0.88 (0.84, 0.92) < 0.001
Family history of diabetes 0.329
 Yes 392 0.66 (0.52, 0.84) < 0.001
 No 14,627 0.80 (0.77, 0.82) < 0.001
Smoking status 0.149
 Current 2872 0.80 (0.74, 0.86) < 0.001
 Past 408 0.78 (0.62, 0.98) < 0.001
 Never 11,739 0.80 (0.76, 0.80) < 0.001
Drinking status 0.170
 Current 390 0.92 (0.78, 1.20) < 0.001
 Past 2027 0.82 (0.72, 0.89) < 0.001
 Never 12,602 0.78 (0.75, 0.81) < 0.001
SBP, mmHg 0.451
 < 140 11,653 0.79 (0.76, 0.82) < 0.001
 ≥ 140 3366 0.78 (0.73, 0.84) < 0.001
DBP, mmHg 0.068
 < 90 12,798 0.79 (0.76, 0.81) < 0.001
 ≥ 90 2221 0.82 (0.75, 0.90) < 0.001

Adjusted for age, sex, family history of diabetes, smoking status, drinking status, SBP, DBP, BMI, FPG, TG, ALT, AST, HDL-C, LDL-C, BUN, and Cr

In each case, the model is not adjusted for the stratification variable