Fig. 3.

Sex-specific differences in the size of atherosclerotic lesion in the aortic arch (A) and aortic sinus (B) after low-dose arsenic, cadmium, and co-exposure in ApoE^−/−mice. All the plaques were smaller than those observed with higher concentrations of arsenic and/or high-fat diet. Plaque was quantified after oil red O staining and imaged using ImageJ. Each point represents a single mouse. Statistical significance is represented as follows: *p < .05; **p < .01; ****p < .0001. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)