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miR-141-3p inhibitors inhibited the ability of ferroptosis resistance in breast cancer cells. (A-B) The expression of SLC7A11 and GPX4 in MCF-7 and MDA-MB-231 cells were observed by Weatern blot assay. (C-D) Measurements of GSH and GSSG content in MCF-7 and MDA-MB-231 cells. (E) JC-1 experiment for visualizing the mitochondrial membrane potential. Scale bar = 50 μm. (F) Measurement of MDA content. (G) IC50 of RSL3 in MCF-7 and MDA-MB-231 cells. *P < 0.05, **P < 0.01.
