Table 3.
Univariate and multivariate Cox regression analyses for overall survival of gastric cancer patients.
| Predictor | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Age, years | ||||
| ≥65 vs <65 | 1.356(0.903-2.036) | 0.142 | ||
| Gender | ||||
| Female vs Male | 1.376(0.910-2.081) | 0.130 | ||
| Size, cm | ||||
| >4cm vs ≤4cm | 1.629(1.054-2.516) | 0.028* | 1.409(0.908-2.185) | 0.126 |
| Tumor location | ||||
| Middle 1/3 vs Upper 1/3 | 1.336(0.635-2.812) | 0.445 | ||
| Lower 1/3 vs Upper 1/3 | 0.859(0.479-1.539) | 0.609 | ||
| More than 2/3 stomach vs Upper 1/3 | 1.097(0.563-2.137) | 0.785 | ||
| Tumor stage (depth of invasion) | ||||
| T3-T4 vs T1-T2 | 0.791(0.366-1.711) | 0.552 | ||
| Lymph node metastasis | ||||
| Positive vs Negative | 2.228(1.332-3.728) | 0.002** | 1.835(1.082-3.112) | 0.024* |
| TNM stage | ||||
| II vs I | 0.815(0.240-2.774) | 0.744 | ||
| III vs I | 1.833(0.577-5.824) | 0.304 | ||
| Lauren type | ||||
| Diffuse vs Intestinal | 1.004(0.623-1.617) | 0.988 | ||
| Expression of SCAMP1 | ||||
| High vs Low | 1.919(1.219-3.021) | 0.005** | 1.638(1.033-2.597) | 0.036* |
HR, Hazard Ratio. pTNM stage is defined using the American Joint Committee on Cancer (AJCC) Staging System, 8th Edition. Asterisks stand for P values as follows: *, P < 0.05; **; P < 0.01.