TABLE 2.
ITT analysis of primary outcome (SCI‐8 post‐intervention)
| Control | dCBT | Adjusted mean difference a (95% CI) | Effect of group | Effect size () | |||
|---|---|---|---|---|---|---|---|
| Baseline | Post‐intervention | Baseline | Post‐intervention | ||||
| Original data | 11.4 (7.0) | 14.9 (7.3) | 12.0 (6.3) | 18.5 (5.9) | −3.661 (−6.14, −1.18) | F 1,64 = 8.72, p = 0.004 | 0.12 |
| Imputation 1 | – | 14.7 (7.0) | – | 18.2 (6.0) | −3.40 (−5.64, −1.16) | F 1,80 = 9.09, p = 0.003 | 0.10 |
| Imputation 2 | – | 14.6 (7.1) | – | 18.5 (6.7) | −3.65 (−5.91, −1.38) | F 1,80 = 10.27, p = 0.002 | 0.11 |
| Imputation 3 | – | 14.8 (7.2) | – | 17.6 (6.7) | −2.77 (−5.09, −0.46) | F 1,80 = 5.67, p = 0.020 | 0.07 |
| Imputation 4 | – | 14.5 (7.1) | – | 18.3 (5.7) | −3.65 (−5.92, −1.37) | F 1,80 = 10.19, p = 0.002 | 0.11 |
| Imputation 5 | – | 14.6 (7.2) | – | 18.1 (6.1) | −3.26 (−5.48, −1.05) | F 1,80 = 8.60, p = 0.004 | 0.10 |
| Pooled | 14.6 | 18.1 | −3.35 | – | – | ||
Note: Data in control and dCBT columns are non‐adjusted means and standard deviations. See Table S2 for estimated marginal means, adjusted for baseline SCI‐8/sex.
Abbreviation: CI, confidence interval; dCBT, digital cognitive behavioural therapy.
a
Mean difference is adjusted for baseline SCI‐8/sex. No data were imputed at baseline.