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GLP-1R antagonists reversed the inhibition of glial cell activation by NJ241. A Iba-1 immunofluorescence showing microglia. B GFAP immunofluorescence indicating astrocytes. Scale bars = 100 μm. C Quantification of Iba-1 positive cells. D Quantification of GFAP fluorescence intensity. n = 5. Data are mean ± SEM. a P < 0.05, aa P < 0.01 vs. control; bb P < 0.01 vs. NJ241; c P < 0.05, cc P < 0.01 vs. NJ241 + MPTP
