Table 4.
Antimicrobial Susceptibility of Carbapenem-Resistant Klebsiella Pneumoniae
| Antimicrobial Agent |
MIC Breakpoints (μg/mL) |
ST11 CR-KP | Non-ST11 CR-KP | χ2 value | P value | ||||
|---|---|---|---|---|---|---|---|---|---|
| (n=52) | (n=33) | ||||||||
| S | I | R | Resistant strains (n) |
Percentage (%) | Resistant strains (n) |
Percentage (%) | |||
| ATM | ≤4 | 8 | ≥16 | 43 | 82.69 | 25 | 75.76 | 0.607 | 0.436 |
| FOX | ≤8 | 16 | ≥32 | 48 | 92.31 | 28 | 84.85 | 1.187 | 0.300 |
| CRO | ≤1 | 2 | ≥4 | 52 | 100.00 | 33 | 100.00 | - | 1.000 |
| FEP | ≤2 | - | ≥16 | 52 | 100.00 | 33 | 100.00 | - | 1.000 |
| CIP | ≤0.25 | 0.5 | ≥1 | 38 | 73.08 | 24 | 72.73 | 0.001 | 0.972 |
| LEV | ≤0.5 | 1 | ≥2 | 44 | 84.62 | 23 | 69.70 | 2.692 | 0.101 |
| IMP | ≤1 | 2 | ≥4 | 52 | 100.00 | 33 | 100.00 | - | 1.000 |
| ETP | ≤0.5 | 1 | ≥2 | 45 | 86.54 | 21 | 63.64 | 6.101 | 0.014 |
| TZP | ≤8/4 | - | ≥32/4 | 45 | 86.54 | 27 | 81.82 | 0.347 | 0.556 |
| SXT | ≤2/38 | - | ≥4/76 | 38 | 73.08 | 25 | 75.76 | 0.076 | 0.783 |
| NIT | ≤32 | 64 | ≥128 | 43 | 82.69 | 19 | 57.58 | 6.453 | 0.011 |
| AMK | ≤4 | 8 | ≥16 | 32 | 61.54 | 8 | 24.24 | 11.272 | 0.001 |
| GEN | ≤2 | 4 | ≥8 | 36 | 69.23 | 8 | 24.24 | 16.364 | 0.001 |
| TOB | ≤2 | 4 | ≥8 | 36 | 69.23 | 21 | 63.64 | 0.286 | 0.593 |
| CZA | ≤8/4 | - | ≥16/4 | 0 | 0.00 | 1 | 3.03 | - | - |
Abbreviations: ATM, aztreonam; FOX, cefoxitin; CRO, ceftriaxone; FEP, cefepime; CIP, ciprofloxacin; LEV, levofloxacin; IMP, imipenem; ETP, ertapenem; TZP, piperacillin/tazobactam; SXT, trimethoprim/sulfamethoxazole; NIT, nitrofurantoin; AMK, amikacin; GEN, gentamicin; TOB, tobramycin; CZA, ceftazidime-avibactam.