Table 2.
Trials Adherence to the SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) Statement
| SPIRIT domain | Bretthauer 2022 (NordICC) | Atkin 2017 (UKFSST) | Holmes 2014 (NORCCAP) | Schoen 2012 (PLCO) | Segnan 2011 (SCORE) | Total % |
|---|---|---|---|---|---|---|
| Administrative information: (total 9), n (%) | 6 (66.7%) | 8 (88.9%) | 8 (88.9%) | 7 (77.8%) | 7 (77.8%) | 80% |
| Introduction: (total 4), n (%) | 4 (100%) | 4 (100%) | 4 (100%) | 4 (100%) | 4 (100%) | 100% |
| Methods:participants, interventions, and outcomes: (total 10), n (%) | 10 (100%) | 10 (100%) | 10 (100%) | 9 (90%) | 10 (100%) | 98% |
| Methods: Assignment of interventions: (total 5), n (%) | 3 (60%) | 4 (80%) | 3 (60%) | 5 (100%) | 4 (80%) | 76% |
| Methods: Data collection, management, and analysis: (total 6), n (%) | 6 (100%) | 6 (100%) | 4 (67%) | 6 (100%) | 6 (100%) | 93.3% |
| Methods: Monitoring: (total 4), n (%) | 4 (100%) | 2 (50%) | 2 (50%) | 4 (100%) | 3 (75%) | 75% |
| Ethics and dissemination: (total 11), n (%) | 9 (81.8%) | 8 (72.7%) | 10 (90.9%) | 11 (100%) | 11 (100%) | 89.1% |
| Appendices: (total 2), n (%) | 1 (50%) | 1 (50%) | 1 (50%) | 1 (50%) | 1 (50%) | 60% |
| Total (51) | 43 (84.3%) | 43 (84.3%) | 42 (82.4%) | 47 (92.2%) | 46 (90.2%) | (86.6%) |
NORCCAP, Norwegian Colorectal Cancer Prevention; NordICC,Nordic-European Initiative on Colorectal Cancer; PLCO, Prostate, Lung, Colorectal, and Ovarian; SCORE, Screening for Colorectal; SPIRIT, Standard Protocol Items: Recommendations for Interventional Trials; UKFSST, United Kingdom Flexible Sigmoidoscopy Screening Trial.