TABLE 2.

Timeline of tests and PND range throughout the study

Day 0 and onward represent tests for statistical comparisons.

Saline Test 1	Saline Test 2	Acute Test 1	Acute Test 2	Saline Test 3	Acute Test 3 (0.32–17.8 mg/kg morphine)	Twice-Daily Injections (3.2–56 mg/kg morphine)	Tolerance Test (3.2–56 mg/kg morphine)	Non-Precipitated Withdrawal
PND 97–99	PND 104–106	PND 111–113	PND 118–120	PND 187–189	PND 194–196	PND 195–214	PND 212–214	PND 213–219
Day −97	Day −90	Day −83	Day −76	Day −7	Day 0	Days 1–18	Day 18	Days 19–24