TABLE 1.
ELISA reactivities of sera from animals immunized with either C4/scbl-V3 or C4/89.6-V3 and challenged with SHIV-89.6 in the first experiment
| Immunogena | Animal no. | Inoculationb | ELISA titerc for peptide:
|
|||
|---|---|---|---|---|---|---|
| C4/scbl-V3 | C4/89.6-V3 | 89.6-V3 | 89.6P-V3 | |||
| C4/scbl-V3 | 206-93 | 3rd | 12,150 | 450 | <50 | <50 |
| 8th | nt | nt | <50 | <50 | ||
| 259-94 | 3rd | 1,350 | 450 | <50 | <50 | |
| 8th | nt | nt | <50 | <50 | ||
| 287-94 | 3rd | 12,150 | 4,050 | <50 | <50 | |
| 8th | nt | nt | <50 | <50 | ||
| 305-94 | 3rd | 1,350 | 1,350 | <50 | <50 | |
| 8th | nt | nt | <50 | <50 | ||
| C4/89.6-V3 | 321-94 | 3rd | 50 | 1,350 | 1,350 | 1,350 |
| 8th | nt | nt | 450 | 1,350 | ||
| 358-95 | 3rd | 150 | 1,350 | 1,350 | 1,350 | |
| 8th | nt | nt | 1,350 | 1,350 | ||
| 539-92 | 3rd | 150 | 1,350 | 1,350 | 1,350 | |
| 8th | nt | nt | 450 | 1,350 | ||
| 556-92 | 3rd | 450 | 1,350 | 1,350 | 1,350 | |
| 8th | nt | nt | 1,350 | 1,350 | ||
a
Animals were inoculated with the designated peptide immunogen.
b
Serum samples were obtained 2 weeks after the designated peptide inoculations. The day of challenge was 2 weeks after the eighth peptide inoculation.
c
Titers are the reciprocals of the highest serum dilutions to score positive. nt, not tested.