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. Author manuscript; available in PMC: 2024 Sep 22.
Published in final edited form as: Cell. 2024 Aug 9;187(19):5267–5281.e13. doi: 10.1016/j.cell.2024.07.020

Figure 4. Integrative structure models and precisions of yeast and mammalian nuclear baskets.

Figure 4.

(A and C) Localization probability density for the yBasket (containing yMlp, yNup1, yNup60, and yNup2 Nups) and mBasket (containing mTpr, mNup50, and mNup153 Nups) obtained from the ensemble of good scoring models. A localization probability density map for a set of models is defined as the probability of observing a model component at any point in space. The yMlps/mTprs (green) are attached to the double NR and NE (light gray half-toroid) with a common interacting FG Nups yNup60/mNup153 (violet).

(B and D) A close-up view of the two subunits of the yBasket and mBasket with model precision for different basket segments. Shown here are yMlp/mTpr (green), FG Nups yNup1 (cyan), yNup2/mNup50 (yellow), and yNup60/mNup153 (violet).

See also Figures S5 and S6.