Table 1.
Clinical and pathological baseline characteristics. Data are shown as median (interquartile range) or absolute numbers (percentage). * Smoking defined as actively smoking or stopped smoking in the last 12 months. ** Tumor size as measured on mammography or MRI. *** Excision volume based on pathologic measurements.
| IOERT, n = 241 |
EB-APBI, n = 164 |
p-value | |||
|---|---|---|---|---|---|
| n; median | %; IQR | n; median | %; IQR | ||
| Age (years) | 69 | 65–73 | 68 | 64–73 | 0.846 |
|
Body mass index (kg/m2) < 25 ≥ 25 Unknown |
97 144 1 |
40 60 0 |
38 126 1 |
23 77 1 |
0.002 |
|
Diabetes mellitus Yes No |
28 213 |
12 88 |
18 146 |
11 89 |
0.968 |
|
Smoking* Yes No |
83 158 |
34 66 |
67 97 |
41 59 |
0.227 |
| Tumor size** (mm) | 12 | 9–16 | 11 | 8–17 | 0.862 |
| Excision volume (mL)*** | 104 | 63–154 | 98 | 63–138 | 0.592 |
|
Tumor location Medial Central/lateral |
59 182 |
25 75 |
43 121 |
26 74 |
0.780 |
|
pT stage Tis T1 T2 |
13 204 24 |
5 85 10 |
22 118 24 |
13 72 15 |
0.004 |
|
pN stage pN0 ≥ pN1mi Unknown |
213 18 10 |
88 8 4 |
138 5 21 |
84 3 13 |
0.001 |
|
Grade 1 2 3 Unknown |
75 98 49 19 |
31 41 20 8 |
49 67 23 25 |
30 41 14 15 |
0.069 |
|
Tumor subtype Luminal HER2+ Triple-negative Unknown |
200 12 13 16 |
83 5 5 7 |
120 9 6 29 |
73 6 4 18 |
0.006 |