Table 1.
Demographics and clinical characteristics for mHNSC-P patients.
| Characteristic | HPV Negative N = 3921 | HPV Positive N = 3431 | p-value2 |
|---|---|---|---|
|
| |||
| Age | > 0.9 | ||
| <=62 | 201 (51%) | 177 (52%) | |
| >62 | 191 (49%) | 166 (47%) | |
| Sex | 0.011 | ||
| Female | 91 (23%) | 54 (16%) | |
| Male | 301 (77%) | 289 (84%) | |
| Race | 0.008 | ||
| Black | 56 (14%) | 38 (11%) | |
| White | 276 (70%) | 290 (85%) | |
| Others | 60 (15%) | 15 (4.4%) | |
| Primary site | <0.001 | ||
| Non-Oropharynx Hypopharynx | 64 (16%) | 18 (5.2%) | |
| Nasopharynx | 78 (20%) | 23 (6.7%) | |
| Oropharynx | 250 (64%) | 302 (88%) | |
| Grade | 0.008 | ||
| I, II | 123 (31%) | 73 (21%) | |
| III, IV | 153 (39%) | 152 (44%) | |
| Unknown | 116 (30%) | 118 (34%) | |
| T stage | 0.8 | ||
| T1, T2 | 103 (26%) | 96 (28%) | |
| T3, T4 | 154 (39%) | 127 (37%) | |
| Unknown | 135 (34%) | 120 (35%) | |
| N stage | <0.001 | ||
| N0, N1 | 105 (27%) | 52 (15%) | |
| N2, N3 | 198 (51%) | 203 (59%) | |
| Unknown | 89 (23%) | 88 (26%) | |
| Insurance | 0.3 | ||
| Insured | 262 (67%) | 251 (73%) | |
| Medicaid | 98 (25%) | 70 (20%) | |
| Uninsured | 23 (5.9%) | 16 (4.7%) | |
| Unknown | 9 (2.3%) | 6 (1.7%) | |
| Marriage | 0.003 | ||
| Married | 158 (40%) | 182 (53%) | |
| Separated | 106 (27%) | 62 (18%) | |
| Unmarried | 105 (27%) | 80 (23%) | |
| Unknown | 23 (5.9%) | 19 (6%) | |
| Treatment | 0.045 | ||
| Comprehensive Treatment a | 210 (54%) | 209 (61%) | |
| Single treatment | 116 (30%) | 96 (28%) | |
| No/Unknown | 66 (17%) | 38 (11%) | |
| Bone | 0.5 | ||
| Yes | 120 (31%) | 98 (29%) | |
| No/Unknown | 272 (69%) | 245 (71%) | |
| Lung | 0.06 | ||
| Yes | 197 (50.2%) | 149 (43%) | |
| No/Unknown | 195 (49.8%) | 194 (57%) | |
| Liver | 0.9 | ||
| Yes | 73 (19%) | 61 (18%) | |
| No/Unknown | 319 (81%) | 273 (82%) | |
| Brain | 0.02 | ||
| Yes | 23 (5.9%) | 8 (2.3%) | |
| No/Unknown | 369 (94.1%) | 335 (97.7%) | |
| Number of metastatic sites | >0.5 | ||
| 1 | 163 (42%) | 151 (44163%) | |
| >=2 | 229 (58%) | 192 (56%) | |
1
n (%);
2
Pearson’s Chi-squared test;
a
two or more than two treatments were given to patients such as chemotherapy plus radiotherapy.