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Effect of anti-CD4 MAb Leu3a on infectivity of pseudotyped virus with NL4-3/SDF1-51 chimeric envelope. U87.CD4.CXCR4 cells were preincubated with the indicated concentrations of anti-CD4 MAb Leu3a or mouse IgG control antibody. After 1 h, NL4-3/WT viruses (A) or NL4-3/SDF1-51 viruses (B) were added to the cells. R.L.U., relative luciferase units.
