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. 2024 Sep 7;7:100200. doi: 10.1016/j.crphar.2024.100200

Table 2.

Detail evaluate of tablets mass, tablets, and dissolution of 4CH2Cl.

Tablet
SSG
PVP K-30
Carr index
Hausner ratio
Hardness
Friability
Disintegrating time
Drug release
Code [mg] [mg] [%] SD SD [kp] SD [%] SD [min.] SD [%] SD
Ta 40.00 16.00 16.10 0.13 1.19 0.01 4.03 0.04 0.47 0.10 0.59 0.10 84.91 0.92
Tb 32.00 24.00 18.75 0.28 1.25 0.01 7.10 0.07 0.57 0.11 1.37 0.09 92.25 0.53
Tc 24.00 32.00 20.45 0.23 1.29 0.01 9.23 0.14 0.66 0.12 7.75 0.13 97.31 0.66
Tp 33.60 22.40 18.00 1.24 6.56 0.55 3.20 90.25
To 33.60 22.40 18.10 0.10 1.24 0.02 6.51 0.22 0.54 0.14 3.30 0.16 90.30 0.54

Tp (prediction tablet): composition and quality prediction follow software design expert.

To (optimum tablet): the composition follows the software design expert, and the quality value is the result of the verification experiment.