Table 2.
Comparisons of demographic and clinical characteristics between patients diagnosed with optic atrophy who developed and who did not develop microcystic macular edema.
| OA+MME | OA-MME | p Value | |
|---|---|---|---|
| Number of patients, n (%) | 69 (16%) | 360 (84%) | |
| Mean age, years (SD) | 44.7 (17.6) | 46.2 (17.8) | 0.52 a |
| Sex, n (% per group) | 0.085 c | ||
| Female | 29 (42%) | 192 (53%) | |
| Male | 40 (58%) | 168 (47%) | |
| Number of eyes, n (%) | 95 (15%) | 548 (85%) | |
| Severity of OA, n (% per group) | 0.12 b | ||
| Moderate | 16 (17%) | 103 (19%) | |
| Severe | 79 (83%) | 445 (81%) | |
| OA topography, n (% per group) | 0.52 b | ||
| Diffuse | 53 (56%) | 318 (58%) | |
| Temporal | 39 (41%) | 185 (34%) | |
| Superior | 2 (2.1%) | 22 (4%) | |
| Nasal | 0 (0%) | 8 (1.5%) | |
| Inferior | 1 (1.1%) | 15 (2.7%) | |
| Mean distance BCVA, logMAR (SD) | 0.62 (0.8) | 0.38 (0.7) | 0.002 a |
| Mean RNFL thickness, μm (SD) | 55.9 (16.4) | 62.5 (14.9) | 0.0001 a |
BCVA: best-corrected visual acuity; logMAR: logarithm of minimum angle of resolution; MME: microcystic macular edema; OA: optic atrophy; RNFL: retinal nerve fiber layer; SD: standard deviation; a: Welch’s t-test; b: Fisher’s exact test; c: Chi-squared test.