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. 2024 Sep 22;16(1):2406539. doi: 10.1080/19420862.2024.2406539

Figure 1.

Plots showing the degree of unfolding as a function of temperature. Most of the variants have lower melting points than wild-type IgG1.

Thermal stability of CD20 antibodies measured by differential scanning fluorimetry. The melt curves (normalized, and offset, first differential) are shown for each sample. The dashed line is aligned with the Tm1 value of the wild-type IgG1 mAb. The corresponding Ton and Tm for the first transition are reported in Table 2.