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. 2024 Sep 23;12(9):e009476. doi: 10.1136/jitc-2024-009476

Table 3. Tumor response.

Total (n=22) InstanCART group (n=7) TraditionCART group (n=15) P value
Objective response, no. (%) 22 (100) 7 (100) 15 (100) 1.00
Months to best response, median (range) 2.0 (1.0–15.0) 2.0 (1.0–3.0) 2.0 (1.0–15.0) 0.58
Best overall response, no. (%) 0.32
 Stringent complete response 12 (55) 3 (43) 9 (60)
 Complete response 2 (9) 0 2 (13)
 Very good partial response 3 (14) 1 (14) 2 (13)
 Partial response 5 (23) 3 (43) 2 (13)
Progression-free survival, months, median (95% CI) 12.0 (7.7 to 16.3) 9.8 (9.0 to 10.6) 15.1 (9.5 to 20.8) 0.10
Overall survival, months, median (95% CI) 16.6 (12.6 to 20.6) Not reached 16.6 (12.0 to 21.2) 0.62
Follow-up time, months, median (95% CI) 12.2 (5.0 to 21.6) 13.5 (5.0 to 17.5) 12.2 (7.2 to 21.6) 0.81

InstanCARTinstant manufacturing platformTraditionCARTtraditional manufacturing process