Table 3. Tumor response.
Total (n=22) | InstanCART group (n=7) | TraditionCART group (n=15) | P value | |
Objective response, no. (%) | 22 (100) | 7 (100) | 15 (100) | 1.00 |
Months to best response, median (range) | 2.0 (1.0–15.0) | 2.0 (1.0–3.0) | 2.0 (1.0–15.0) | 0.58 |
Best overall response, no. (%) | 0.32 | |||
Stringent complete response | 12 (55) | 3 (43) | 9 (60) | |
Complete response | 2 (9) | 0 | 2 (13) | |
Very good partial response | 3 (14) | 1 (14) | 2 (13) | |
Partial response | 5 (23) | 3 (43) | 2 (13) | |
Progression-free survival, months, median (95% CI) | 12.0 (7.7 to 16.3) | 9.8 (9.0 to 10.6) | 15.1 (9.5 to 20.8) | 0.10 |
Overall survival, months, median (95% CI) | 16.6 (12.6 to 20.6) | Not reached | 16.6 (12.0 to 21.2) | 0.62 |
Follow-up time, months, median (95% CI) | 12.2 (5.0 to 21.6) | 13.5 (5.0 to 17.5) | 12.2 (7.2 to 21.6) | 0.81 |
InstanCARTinstant manufacturing platformTraditionCARTtraditional manufacturing process