Fig. 6. RMSF analysis of GSK3β backbone atoms. The root-mean-square fluctuation (RMSF) of the GSK3β backbone atoms in the MD systems is shown. The L12 and L21 regions are highlighted with blue and yellow shades, respectively, for clarity. The residue index starts from the first residue, Ser35. Adjacent to the RMSF panel are the overlapped structures from the MD simulation, where proteins are shown as tubes colored from red (0 ns) to blue (200 ns). Ligands are represented by balls and sticks.