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. 2024 Sep 23;8(13):CASE2451. doi: 10.3171/CASE2451

TABLE 1.

Characteristics, symptomatology, and management of patients with intracranial hypertension secondary to neuroborreliosis treated surgically

Authors & Year Patient Age (yrs) Patient Sex Symptoms & Physical Findings Surgical Treatment(s) Medical Treatment(s) Outcome(s)
Lochhead & Thompson, 200112 7 F Bilat papilledema, visual loss, headache, back pain, emesis, rt cranial nerve VII palsy Serial LPs Ceftriaxone, methylprednisolone, acetazolamide Complete resolution of papilledema, partial improvement of visual acuity, remaining optic nerve atrophy
Nord & Karter, 200313 37 M Headache, myalgias, fever, fatigue Serial LPs Doxycycline Complete symptom resolution after 3 LPs over 10 days
Moussawi et al., 201614 20 M Bilat papilledema, diplopia, cranial nerve VI palsy, meningismus Serial LPs Ceftriaxone, acetazolamide Complete symptom resolution in 1 mo
Rogers et al., 20234 5 F Bilat papilledema, diplopia, headache, emesis Lumbar drain Amoxicillin, ceftriaxone, furosemide, acetazolamide Resolution of papilledema in 55 days, remaining retinal nerve atrophy
Rogers et al., 20234 6 M Bilat papilledema, diplopia, cranial nerve VI palsy, headache Lumbar drain Cefepime, doxycyline, ceftriaxone, methylprednisolone, furosemide, acetazolamide Complete symptom resolution by 61 days, recurrence of asymptomatic papilledema at follow-up, acetazolamide led to complete resolution again at 56 days postrecurrence
Nørreslet Gimsing & Lunde Larsen, 202018 51 F Bilat papilledema, visual loss, headache, emesis, dizziness, tinnitus Serial LPs, VP shunt Ceftriaxone, acetazolamide Serial LPs provided relief w/ recurrence after 3 wks, shunting halted symptom progression w/ resolution by 6 mos, remaining optic nerve atrophy, central scotoma, & loss of color vision
Rothermel et al., 200116 11 M Bilat papilledema, optic neuritis, diplopia, cranial nerve VI palsy, cranial nerve VII palsy, meningismus, hyporeflexia VP shunt Doxycycline, ceftriaxone, methylprednisolone Resolution of papilledema by 6 mos, remained blind in both eyes