Figure 1.

Schematic of an eye cross-section with an enlarged view of posterior sclera (blue), lamina cribrosa (black), retrolaminar neural tissue (grey), dura mater (red) and pia mater (purple) regions highlighted at the ONH. Boundary conditions included forces from IOP and displacements at the periphery. (b) Example images of serial coronal sections through the ONH of a pig eye from the anterior to posterior side. PLM was used to determine the collagen fiber orientation at each pixel [38]. Colors in the images indicate in-plane fiber orientation. Brightness indicates the strength of the signal. Low signal occurs when there is no birefringent material, no collagen, or the signal is blocked, for instance by pigment. The pig lamina cribrosa and scleral canal are elliptical with the major axis along the Nasal- Temporal (N-T) direction and the minor axis along the inferior-superior (I-S) direction. The Sections were stacked sequentially to construct a fiber model for modelling the collagenous tissues in the ONH region [1]. (c) Longitudinal cut-model view of the fiber model along the I-S direction with only bundle centerlines shown. (d) An isometric view of the complete fiber model with full bundle width displayed.