Figure 2.

Schematic illustration of the geometry and boundary conditions of the fiber model and the continuum models. The same boundary conditions were applied to both models to simulate an inflation experiment. The continuum model was meshed using quadratic 10-nodded, tetrahedral mixed-formulation elements (C3D10H in Abaqus). A coarser mesh was selected for the peripheral sclera while a finer mesh was generated for the region where the peripapillary sclera, laminar cribrosa, neural tissue, pia mater and dura mater are located. After a mesh refinement analysis, it was decided that a mesh with ~78,000 elements and element size ranging from 0.1mm to 0.25mm was used for the simulation.