Figure 6.

(A) Schematic illustration summarizing the inner junction components in three regions of the cilium. In poc1Δ, the axoneme-specific MIPs are in red; note that many BB components are partially bound in the mutant as the inner junction structure is disrupted without Poc1. (B) A model illustrates the poc1Δ BB A-B inner junction partially morphing into an axoneme-like architecture. The double-ended arrows indicate expansion of the inner junction gap as PACRG and FAP20 are incorporated in. This causes the disassociation of Poc39 and facilitates the binding of axonemal components, such as CCDC81b and BMIP1.