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. 2024 Sep 11;20(9):e1011093. doi: 10.1371/journal.pgen.1011093

Fig 6. Bar charts of gene ontology (GO) analysis of cellular component for MEF2C direct target gene-sets using the ClueGo plugins of Cytoscape.

Fig 6

The Bonferroni method was applied for a p-value correlation (p < 0.05). The vertical axis displays the names of the GO terms. The horizontal axis and bar lengths represent the significance [−log10 (p-value)]. Colors in the bars represent different MEF2C direct target gene-sets. Results are presented only for the five gene-sets that were previously enriched for common variation associated with SCZ, IQ and/or EA. Enriched terms that were related to each other in the ontology were grouped together, with the most significant term(s)/group displayed. All data is detailed in S16–S23 Tables. NSCs: Neural stem cells; iNs: induced neurons; DELhom: Homozygous deletion; DELhet: Heterozygous deletion; PB: Proximal Boundary.