Table 1. Number of DEGs in each gene-set before and after the integration with MEF2C ChIP-seq data to identify direct target genes.
| Gene-Set | # of all DEGs | # of MEF2C Direct Targets (% of MEF2C Direct Targets relative to all DEGs) |
|---|---|---|
| NSCs | ||
| DELhet | 366 | 169 (46%) |
| DELhom | 2187 | 1170 (53%) |
| DELhet_PB | 492 | 240 (49%) |
| DELhom _PB | 728 | 412 (57%) |
| iNs | ||
| DELhet | 689 | 335 (51%) |
| DELhom | 291 | 145 (50%) |
| DELhet_PB | 2980 | 1034 (35%) |
| DELhom _PB | 5132 | 1174 (23%) |
NSCs: Neural stem cells; iNs: Induced neurons; DELhom: Homozygous deletion; DELhet: Heterozygous deletion; PB: Proximal boundary (indirect mutation of MEF2C).