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. 2024 Sep 4;27(10):110885. doi: 10.1016/j.isci.2024.110885

Figure 1.

Figure 1

Conceptual overview of the AMC chips inducing discrete and directed growth of neurons based on AMCs inspired by the cerebral aqueduct

(A) Schematic of the cerebral aqueduct and its cross-section.

(B) Driving principle of the hydrostatic pressure in the AMCs for the discrete directed growth of primary cortical neurons (PCNs).

(C) Experimental process of the discrete directed growth of the PCNs in the AMCs under fluid pressure regulation.