Table 4. Clinical implementation of whole genome sequencing.
| Clinical implementation | Total (N = 80) | Whole genome sequencing | P value | ||
|---|---|---|---|---|---|
| Diagnosed (n = 21) | Undiagnosed (n = 59) | ||||
| Duration of NICU admission, days | 46 (22–97) | 47 (17–102) | 41 (23–90) | 0.933 | |
| Death | 9 (11.3) | 3 (14.3) | 6 (10.2) | 0.691 | |
| Start of target medication | 1 (1.3) | 1 (4.8) | 0 (0.0) | 0.262 | |
| Surgery | 63 (78.8) | 15 (71.4) | 48 (81.4) | 0.363 | |
| Before NICU discharge | 51 (63.8) | 10 (47.6) | 41 (69.5) | 0.107 | |
| Rehabilitation | 52 (65.0) | 18 (85.7) | 34 (57.6) | 0.032* | |
| Tracheostomy | 4 (5.0) | 1 (4.8) | 3 (5.1) | 1.000 | |
| Gastrostomy | 12 (15.0) | 7 (33.3) | 5 (8.5) | 0.011* | |
| Genetic counselling | 19 (23.8) | 15 (71.4) | 4 (6.8) | < 0.001* | |
| Long term follow-up | 65/75 (86.7) | 17/19 (89.5) | 48/56 (85.7) | 1.000 | |
Values are presented as number (%) or median (interquartile ranges).
NICU = neonatal intensive care unit.
*P < 0.05.