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. 2024 Sep 10;18:1435218. doi: 10.3389/fnins.2024.1435218

Table 3.

Macrostructural analysis.

Fazekas Reviewer 1 Reviewer 2
Grade 0 Grade 1 Grade 2 Grade 0 Grade 1 Grade 2
Controls 8 25 3 15 19 2
Patients 8 25 3 18 16 2
p = 1.00 p = 0.77
GCA Grade 0 Grade 1 Grade 2 Grade 0 Grade 1 Grade 2
Controls 2 32 2 29 7 0
Patients 2 32 2 35 1 0
p = 1.00 p = 0.972
Cortical infarcts 0 1 or more 0 1 or more
Controls 35 1 36 0
Patients 34 2 36 0
p = 0.5 NA
Lacunar infarcts 0 1 or more 0 1 or more
Controls 36 0 35 1
Patients 32 4 35 1
p = 0.057 p = 0.75
Microbleeds 0 1 or more 0 1 or more
Controls 32 4 35 1
Patients 32 4 34 2
p = 0.65 p = 0.5

Comparisons of white matter changes (Fazeka), global cerebral atrophy (GCA), cortical infarcts, lacunar infarcts, and microbleeds between controls and patients for both reviewers. No significant differences were observed.